To be honest, I've always found that the people who tend to send stroppy messages back to recruiters or simply 'UNSUBSCRIBE' tend to be the most difficult of candidates as well when they are looking for a role in the future. A simple, 'please remove me from your mailing list' goes a long way.
Yes, I work in recruitment, but I also appreciate people trying to make a living, I get regular emails from people/companies trying to sell me things and I genuinely don't mind at all.